Blackpool travel down to take on Reading.
The Seasiders defeated Barnsley 3-2 last weekend with goals coming from Sonny Carey, James Husband and Hayden Coulson.
Reading lost 3-2 to Burton Albion who are in a relegation battle.
The two sides have met this season where Blackpool came out 4-1 winners with Jordan Rhodes scoring a hat-trick.
The Royals sit comfortably in 17th despite having a point deduction and they will be playing in League One next season.
It is a very huge game for the Tangerines as they must win to seek a chance of the play-offs as they need at least two teams not to win which includes the likes of Lincoln,Oxford and Barnsley.
Over 1,600 Seasiders will be making the trip down south in a hope that Blackpool will reach a play-off spot.